Parallel sequential reactor

Details Parallel sequential reactor Parallel sequential reactor

1992-10-30

1994-02-22

Warden, Robert J.

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

Sensed condition is operating time and control is operation...

422 63, 435287, 435289, 935 88, C12M 100, G05B 1300

Patent

active

052884686

ABSTRACT:
A reactor for sequentially modifying a molecule attached to a solid phase support, including: a plurality of substrate carriers, each substrate carrier capable of carrying a solid phase support to which a molecule to be modified can be attached; a plurality of reagent chambers, each capable of comprising a reagent for effecting a modification of the molecule; and means for individually bringing each of a plurality of chosen substrate carriers into a reagent-contact mode and a reagent-non-contact mode with each of a plurality of reagent chambers. Each of a plurality of the substrate carriers is capable of sequential contact with the contents of a plurality of the reagent chambers. The sequential contact is capable of resulting in the sequential modification of molecules attached to solid phase supports on the plurality of substrate carriers.

REFERENCES:
patent: 3531258 (1970-09-01), Merrifield et al.
patent: 4353989 (1982-10-01), Bender et al.
patent: 4373071 (1983-02-01), Itakura
patent: 4483964 (1984-11-01), Urdea et al.
patent: 4517338 (1985-05-01), Urdea et al.
patent: 4598049 (1986-07-01), Zelinka et al.
patent: 4668476 (1987-05-01), Bridgham et al.
patent: 4671941 (1987-07-01), Niina et al.
patent: 4746490 (1988-05-01), Saneii
patent: 4748002 (1988-05-01), Neimark et al.
patent: 4952518 (1990-08-01), Johnson et al.
Alvarado-Urbina et al., Science 214:270-274, 1981.
Caruthers et al., Methods in Enzymology 154:287-313, 1987.
Djurhuss Matthes et al., Methods in Enzymology 154:250-285, 1987.
Fodor et al., Science 251:767-773, 1991.
Frank et al., Methods in Enzymology 154:221-249, 1987.
Geysen et al., Journal of Immunological Methods 102:259-274, 1987.
Hultman et al., Nucleosides and Nucleotides 7:629-638, 1988.
Geysen et al., Ciba Foundation Symposium 119:130-149, 1986.
Itakura et al., Ann. Rev. Biochem. 53:323-56, 1984.
Schnorrenberg and Lang, Proceedings of the Eleventh American Peptide Symposium, Jul. 9-14, 1989, Ed Rivier and Marshall, pp. 1029-1030, 1989.

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