Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2006-03-21
2006-03-21
Lee, John R. (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C250S281000, C250S282000, C250S287000, C250S42300F, C250S424000, C250S425000, C436S518000, C436S519000, C427S421100, C427S422000, C210S198200, C210S656000, C210S659000
Reexamination Certificate
active
07015465
ABSTRACT:
A method and apparatus for the continuous deposition of RP HPLC eluent, from isocratic or gradient elutions, on to a MALDI target using a parallel sample desalting method, allows increased sensitivity of the MALDI sample by pre-concentration of the analyte, separation of interfering contaminants from the analyte and increased dynamic range of peptide abundance that can be analyzed. The parallel processing of sample material allows greater throughput than that of manual methods.
REFERENCES:
patent: 5376277 (1994-12-01), Cortes et al.
patent: 5770272 (1998-06-01), Biemann et al.
patent: 5772964 (1998-06-01), Prevost et al.
patent: 6175112 (2001-01-01), Karger et al.
patent: 6296771 (2001-10-01), Miroslav
patent: 6358692 (2002-03-01), Jindal et al.
patent: 6410914 (2002-06-01), Park et al.
patent: 6436292 (2002-08-01), Petro
patent: 6491816 (2002-12-01), Petro
patent: 6633031 (2003-10-01), Schultz et al.
patent: 6653627 (2003-11-01), Guevremont et al.
patent: 6776902 (2004-08-01), Petro
patent: 6818134 (2004-11-01), Lemmon et al.
patent: 6858435 (2005-02-01), Chervet et al.
patent: 2002/0020670 (2002-02-01), Petro
patent: 2002/0190001 (2002-12-01), Petro
patent: 2003/0070988 (2003-04-01), Petro et al.
patent: 2004/0084374 (2004-05-01), Lemmon et al.
patent: 2004/0262513 (2004-12-01), Karol et al.
K. Wagner, et al, Protein mapping by two-dimensional high performance liquid chromatography, Journal OFChromatography, A, 893 (2000) 293-305.
Finch Jeffrey
Karol Robert
Wall Daniel
Brown Rudnick Berlack and Israels LLP
Lee John R.
Souw Bernard E.
Waters Investments Limited
LandOfFree
Parallel concentration, desalting and deposition onto MALDI... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Parallel concentration, desalting and deposition onto MALDI..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Parallel concentration, desalting and deposition onto MALDI... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3583426