Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-07-28
1991-12-24
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
435119, 435933, 544338, A61K 31495, C12P 1718, C07D24136
Patent
active
050753070
ABSTRACT:
Paraherquamide and dihydroparaherquamide, known compounds, are disclosed as having antiparasitic activity. The compounds are fungal metabolites isolated from the known fungus Penicillium paraherquei, and from a newly isolated strain of Penicillium charlesii. Compositions including paraherquamide and dihydroparaherquamide as the active ingredient thereof for antiparasitic uses against endo and ecto parasites are also disclosed, as well as processes for the preparation of paraherquamide from the newly isolated fungus.
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Okuyama et al., Tetrahedron LeH, vol. 24, pp. 3113-3114, 1983.
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Verrall, M., "Discovery and Isolation of Microbial Products", 1985, pp. 17-24 and 37-39.
Matas Maria T. D.
Moohales del Val Sagrario
Ostlind Dan A.
Punsola Luis
DiPrima Joseph F.
Marx Irene
Merck & Co. , Inc.
Robinson Douglas W.
Rose David L.
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