Para-hydroxyalkylation of hydroxylated aromatic compounds

Details Para-hydroxyalkylation of hydroxylated aromatic compounds Para-hydroxyalkylation of hydroxylated aromatic compounds

1993-07-12

1995-07-04

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 6501

Patent

active

054301831

ABSTRACT:
Hydroxylated aromatic compounds devoid of substituents in the para-position to the hydroxyl group thereof are para-hydroxyalkylated, e.g., into optionally substituted p-hydroxymandelic acid compounds, more particularly p-hydroxymandelic acid and 3-methoxy-p-hydroxymandelic acid, by condensing same with an organic carbonyl compound in the presence of a quaternary ammonium hydroxide.

REFERENCES:
patent: 4329497 (1982-05-01), Kaniss et al.
Patent Abstracts of Japan, vol. 12, No. 491 (C-554)(3338) 21 Dec. 1988, & JP-A-63 203 631 (Nippon Kayaku Co. Ltd.) Aug. 23, 1988.

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