para-alkyl-substituted...

Details para-alkyl-substituted... para-alkyl-substituted...

2007-02-12

2009-06-02

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C514S616000

Reexamination Certificate

active

07541495

ABSTRACT:
para-Alkyl-substituted N-(4-hydroxy-3-methoxybenzyl)-cinnamic acid amide compounds, processes for the preparation thereof, pharmaceutical compositions containing these compounds, and the use of these compounds for treating or inhibiting specific diseases or disorders.

REFERENCES:
patent: WO 91/16892 (1991-11-01), None
patent: WO 97/45400 (1997-12-01), None
patent: WO 02/076946 (2002-10-01), None
patent: WO 03/092676 (2003-11-01), None
T. Wayne Schultz et al., “Structure-Activity Relationships for Osteolathyrism: II. Effects of Alkyl-Substituted Acid Hydrazides”, Toxicology 53, (1988) pp. 147-159, Elsevier Scientific Publishers Ireland Ltd.
T. Sudhakar Johnson et al., “Precursor Biotransformation in Immobilized Placental Tissues of Capsicum frutescens Mill.:II. Influence of Feeding Intermediates . . . ”, J. Plant Physiol., (1998) pp. 240-243, vol. 153.
Antonio Ferrer-Montiel et al., “Molecular architecture of the vanilloid receptor insights for drug design”, Eur. J. Biochem. 271, (2004), pp. 1820-1826.
Christopher S.J. Walpole et al., “Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents; Structure-Activity Studies. 3. The Hydrophobic Side-Chain C-Region”, J. Med. Chem. 1993, 36, pp. 2381-2389.
Arpad Szallasi et al., “Vanilloid (Capsaicin) Receptors and Mechanisms”, The American Society for Pharmacology and Experimental Therapeutics, Pharmacological Reviews, 1999, vol. 51, No. 2, pp. 159-211.
Form PCT/IPEA/409 w/English translation (Eleven (11) pages).
International Search Report dated Dec. 5, 2005 w/English translation of pertinent portion (Two (2) pages).
German Search Report dated Jan. 19, 2005 w/English translation of pertinent portion (Eight (8) pages).

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