Panel of antibodies for detecting cadherins and catenins in tiss

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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4241301, G01N 33574, A61K 39395

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active

058957480

ABSTRACT:
There is provided an antibody-based panel for detecting the cadherin family of proteins, the catenin family of proteins and the plaque family of proteins in tissues for the diagnosis and prognostic assessment of human tumors. The panel includes a set of antibody reagents, each antibody reagent is capable of recognizing a specific protein where the protein is a member of either the general cadherin family of proteins, the general catenin family of proteins or the general plaque family of proteins.

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Geiger B. et al., Broad spectrum pan-cadherin antibodies, reactive with the C-terminal 24 amino acid residues of N-caderin, J. Cell Sci. 97:607-614, 1990.

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