Pancreatic secretory tryspin inhibitor and variants thereof prod

Details Pancreatic secretory tryspin inhibitor and variants thereof prod Pancreatic secretory tryspin inhibitor and variants thereof prod

1991-04-16

1992-06-30

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 9, 514 2, 930250, 930260, 930270, 530324, 530325, 530350, 435 692, 435 691, A61K 3702, C07K 710, C07K 764

Patent

active

051263220

ABSTRACT:
The present invention relates to a peptide having essentially the amino acid sequence of pancreatic secretory trypsin inhibitor (PSTI). The present invention also relates to variants of such peptide wherein one or more of the amino acids in the original sequence are replaced by other amino acids. These peptides show an advantageously modified specificity in their inhibotory action. A method of preparation of the peptides and their pharmaceutical use is also described.

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