Pancreas dependant immunoassay for determining subpopulations of

Chemistry: analytical and immunological testing – Involving production or treatment of antibody – Monoclonal antibody

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435 7, 424 85, 436817, G01N 33567, G01N 33577, A61K 3704

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047644753

ABSTRACT:
A correlation has been demonstrated between the ability of an antibody to block the inhibitory action of somatostatin on the gastric inhibitory peptide(GIP)-stimulated release of insulin from the pancreas in vitro and the ability to stimulate growth in vivo. Antibodies which are identified in the GIP-stimulated insulin release assay are also capable of elevating the levels of growth hormone in vivo.

REFERENCES:
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patent: 4599229 (1986-07-01), Maccecchini
McIntosh et al., Chem. Abstracts 94:202973w (for Can. J. Phys. Pharmacol., 59(5), 468, (1981)).
McIntosh et al., Chem. Abstracts, 90:68566c (for Z. Gastroenterol., 16(5), 330, (1970)).
McIntosh et al., Chem. Abstracts, 89:127026f (for Gut Hormone, (1978), 453-6, Bloom (ed)).

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