Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2010-01-22
2010-10-05
Kosar, Andrew D (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
Reexamination Certificate
active
07807635
ABSTRACT:
A method of inhibiting protein kinases by administering polypeptides derived from alpha-neurotoxin, and inhibiting protein kinases. Diseases treated thereby include cancer, influenza, Tourette's syndrome, pain, and neurological deficits.
REFERENCES:
patent: 7259237 (2007-08-01), Miller et al.
patent: 7348400 (2008-03-01), Livett et al.
patent: 2006/0088843 (2006-04-01), Reid
patent: 2006/0088858 (2006-04-01), Reid
patent: 2007/0190167 (2007-08-01), Reid et al.
patent: 2008/0081048 (2008-04-01), Raymond et al.
patent: 2008/0107752 (2008-05-01), Reid et al.
patent: 2008/0161538 (2008-07-01), Miller et al.
patent: 2008/0248992 (2008-10-01), Mundschenk et al.
H.R. Mundy et al. Neurology. (2003) 61, pp. 528-530.
I. Kasheverov et al. J. Recept. Signal Trans. Res. (1999) 19(1-4), pp. 559-571.
Z. Chen et al. Acta Pharm. Sin. (2006) 27(4), pp. 402-408.
I.N. Utkin et al. Bioorg. Khim. (1999) 25(11), pp. 805-810.
Sanders, M., Soret, M.G., Akin, B.A., Neurotoxoid interference with two human strains of poliomyelitis in Rhesus Monkeys. Ann. N.Y. Acad. Sci. (1953) 58: 1-12.
Lamb, G., Hunter, W.K., On the action of venoms of different species of poisonous snakes on the nervous system. Lancet (1904) 1: 20-22.
Bodian, D. and Howe, HA. The rate of progression of poliomyelitis virus in nerves. Bulletin of the Johns Hopkins Hospital (1941) 69: 79-85.
Wright, E. A., Morgan, R. S. and Wright, G. P., The movements of toxin in the nervous system in experimental tetanus in rabbits, Brit. J. Exp. Path., (1951) 32: 169-182.
van Heyningen, W.E., Miller, P.A., J. Gen. Microbiol., The fixation of tetanus toxin by ganglioside. (1961) 24: 107-119.
Miller, K.D., Miller, G.G., Sanders, M., Fellowes, O.N. Inhibition of virus-induced plaque formation by atoxic derivatives of purified cobra neurotoxins. Biochim. Biophys. Acta (1977) 496: 192-196.
Yourist, J.E., Haines, H.G., and Miller, K.D., Inhibition of Herpes Simplex Virus Replication by Cobra -Neurotoxoid. J Gen Virol. (1983) 64: 1475-1481.
Neri P, Bracci L, Rustici M, Santucci A., Sequence homology between HIV gp120, rabies virus glycoprotein, and snake neurotoxins. Is the nicotine receptor a HIV receptor? Arch Virol. (1990) 114: 265.
Bracci,L., Ballas, SK., Spreafico, A., Neri, P., Molecular Mimicry Between the Rabies Virus Glycoprotein and Human Immunodeficiency Virus-1 GP120: Cross-Reacting Antibodies Induced by Rabies Vaccination Blood, (1997) 90: 3623-3628.
Gordon, A.S., Davis, C.G., Milfray, D., Diamond, I. Phosphorylation of acetylcholine receptor by endogenous membrane protein kinase in receptor-enriched membranes of Torpedo californica. Nature (1977) 267: 539-540.
Gordon, A.S., Davis, C.G., Diamond, I., Phosphorylation of Membrane Proteins at a Cholinergic Synapse,Proc. Natl. Acad. Sci. (1977) 263-267.
Teichberg,V.I., Sobel, A., Changeux, J.P., In vitro phosphorylation of the acetylcholine receptor. Nature (1977) 267: 540-542.
Saitoh, T., Changeux, J.P., Change in state of phosphorylation of acetylcholine receptor during maturation of the electromotor synase in Torpedo marmorata electric organ. Proc. Natl. Acad. Sci., (1081) 78: 4430-4434.
Huang KP, Robinson JC. A rapid and sensitive assay method for protein kinase. Anal. Biochem. (1976) 72: 593-599.
Fabricant, RN, DeLarco, JE, Todaro, GJ. Nerve growth factor receptors on human melanoma cells in culture. Proc Natl Acad Sci USA (1977) 74: 565-569.
Iida, J., Skubitz, A.P.N., McCarthy, J.B., Skubitz, K.M., Protein kinase activity is associated with CD63 in melanoma cells. J Transl Med. (2005) 3: 42-50.
Nambiar, S., Mirmohammadsadegh, A., Doroudi, R., Gustrau, A., Marini, A.,Roeder, G., Ruzicka, T., Hengge, U.R., Signaling Networks in Cutaneous Melanoma Metastasis Identified by Complementary DNA Microarrays. Arch Dermatol. (2005) 141: 165-173.
Selzer, E., Okamoto, I.., Lucas, T., Kodym, R.., Pehamberger, H., Jansen, B. Protein kinase C isoforms in normal and transformed cells of the melanocytic lineage. Melanoma Research. (2002) 12: 201-209.
Crawford, P.C., Dubovi, E.J., Castleman, W.L., Stephenson, Gibbs, E.P.J., Chen, L., Smith, C., Hill, R.C., Pamela Ferro, Pompey, J., Bright, R.A., Medina, M-J. Transmission of Equine Influenza Virus to Dogs. Science (2005) 310: 482-485.
Yoon K-J, Cooper VL, Schwartz KJ, Harmon KM, Kim W-I, Janke BH, et al. Influenza virus infection in racing greyhounds. Emerg Infect Dis. (2005) 11: 1974-1976.
Lentz, Thomas L., Structure-Function Relationships of Curaremimetic Neurotoxin Loop 2 and of a Structurally Similar Segment of Rabies Virus Glycoprotein in Their Interaction with the Nicotinic Acetylcholine Receptor. Biochem. (1991) 30: 10949-10957.
Austin Billy S.
Miller Kent D.
Kohn & Associates PLLC
Kosar Andrew D
LandOfFree
Pan-antiviral peptides for protein kinase inhibition does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pan-antiviral peptides for protein kinase inhibition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pan-antiviral peptides for protein kinase inhibition will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4241886