Pan-antagonists for the androgen receptor and androgen...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C558S413000

Reexamination Certificate

active

07550505

ABSTRACT:
Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriate activation of the androgen receptor.

REFERENCES:
patent: 4636505 (1987-01-01), Tucker
patent: 5872150 (1999-02-01), Elbrecht et al.
patent: 6071957 (2000-06-01), Miller et al.
patent: 7057048 (2006-06-01), Du et al.
Murata, M. et al., “A General And Efficient Method For The Palladium-Catalyzed . . .”, Tetrahedron, 60 (2004), pp. 7397-7403.
Zheng, N. et al., “Palladium-Catalyzed Synthesis Of Aryl Sulfides . . .”, J. Org. Chem. 1998, 63, pp. 9606-9607.
Chen, B. et al., “Nucleophilic Aromatic Substituion Of Methacrylamide Anion . . .”, J. Org. Chem. 2003, 68, pp. 10181-10182.
Tucker, H. et al., “Nonsteroidal Antiandrogens, Synthesis And Structure . . .”, J. Med. Chem. 1998, 31, pp. 954-959.
Friden, PM et al., “Blood-Brain Barrier Penetration And In Vivo Activity Of An NGF . . .”, Science, vol. 259, Issue 5093, pp. 373-377.
Davis, FF et al., “Enzyme-Polyethylene Glycol Adducts . . .”, Enzyme Engineering, vol. 4, pp. 169-173.
Burnham, NL, “Polymers For Delivering Peptides And Proteins”, Amer. J. Health-System Pharmacy, 1994, 51 (2), pp. 210-218.
Amselem, S. et al., “In Vitro Tests To Predict In Vivo Performance . . .”, Chemistry And Physics Of Lipids, 64 (1993), pp. 219-237.
Hara, T. et al., “Novel Mutations Of Androgen Receptor . . .”, Cancer Research, 63 (2003), pp. 149-153.
McGinley, P.et al., Circumventing Anti-Androgen Resistance by Molecular Design. J. Am. Chem. Soc. 129, 3822-3823, 2007.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Pan-antagonists for the androgen receptor and androgen... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pan-antagonists for the androgen receptor and androgen..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pan-antagonists for the androgen receptor and androgen... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4057894

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.