Palatable oral suspension and method

Details Palatable oral suspension and method Palatable oral suspension and method

2007-02-13

2007-02-13

Tran, S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C514S312000

Reexamination Certificate

active

10386199

ABSTRACT:
A drug formulation in the form of a dry powder is provided which when mixed with water forms a palatable oral suspension substantially free of bitter taste, the dry powder being formed of a drug, preferably des-quinolone, which in solution has a bitter taste, and a pH modifying agent which is preferably an alkaline material such as L-arginine, where upon mixing the dry-powder in water causes the drug to have reduced solubility or precipitate in-situ to form a palatable oral suspension essentially free of bitter taste.An oral suspension, methods for making same and a method for masking the bitter taste of drugs employing one or more pH modifying agents are also provided.

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Remington's Pharmaceutical Sciences, 18thed., 1990, pp. 1290-1292.

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