Palatable ibuprofen solutions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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Details

514570, 514781, 514974, A01N 4304, A01N 3710, A01N 2500

Patent

active

050249975

ABSTRACT:
Palatable ibuprofen aqueous base solutions are described which contain dissolved therein ibuprofen and hydroxypropyl beta cyclodextrin, which form an inclusion complex, and sweeteners to mask the sour taste common to organic acids.

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CA 111(3): 23899z-Markarian et al.
CA 112(12): 104681v-Menard et al.
F. A. Menard et al, "Potential Pharmaceutical Applications of a New Beta Cyclodextrin Derivative", Drug Development and Industrial Pharmacy, 14(11), 1529-1547 (1988).
Orienti, Isabella et al, "Availability of NSAIDH .beta.-Cyclodextrin Inclusion Complexes", Arch. Pharm. (Weinheim) 322, 207-211 (1989).

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