Pain treatment by peripheral administration of a neurotoxin

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S236100, C424S009100, C514S002600, C514S012200, C530S350000, C435S252700

Reexamination Certificate

active

06869610

ABSTRACT:
Methods for treating a non-spasm caused pain by peripheral administration to a patient of a therapeutically effective amount of a neurotoxin, such as a botulinum toxin.

REFERENCES:
patent: 5714468 (1998-02-01), Binder
patent: 5766605 (1998-06-01), Sanders et al.
patent: 5989545 (1999-11-01), Foster et al.
patent: 6063768 (2000-05-01), First
patent: 6113915 (2000-09-01), Aoki
patent: 6261572 (2001-07-01), Donovan
patent: 6464986 (2002-10-01), Aoki et al.
patent: 9415629 (1994-07-01), None
patent: WO 9530431 (1995-11-01), None
patent: 9633273 (1996-10-01), None
patent: WO 9734624 (1997-09-01), None
patent: 9807864 (1998-02-01), None
patent: 9917806 (1999-04-01), None
Barwood, Shane, et al;Analgesic Effects of Botulinum Toxin A: A Randomized, Placebo-Controlled Clinical Trial; Developmental Medicine & Child Neurology, 2000; 42:116-121.
Bigalke, H., et al.;Botulinum A Neurotoxin Inhibits Non-Cholinergic Synaptic Transmission in Mouse Spinal Cord Neurons in Culture; Brain Research, 360 (1985); 318-324.
Bigalke, H., et al.;Tetanus Toxin and Botulinum A. Toxin Inhibit Release and Uptake of Various Transmitters, as Studied with Particulate Preparations from Rat Brain and Spinal Cord; Naunyn-Schmiedeber's Arch. Pharmacol(1981); 316:244-251.
Cheshire, et al.;Botulinum Toxin in the Treatment of Myofascial Pain Syndrome; Pain, 1994; 59(1):65-9.
DiStefano, P. S., et al.;Receptor Mediated Retrograde Axonal Transport of Neurotrophic Factors is Increased After Peripheral Nerve Injury; Progress in Brain Research(1994); vol. 103; Chapter 4; 35-42.
Cheng, Guang-Shing;Botox, Dermabrasion Treated Facial Leiomyomas; Skin & Allergy News2000;31(3):16.
First, E. et al.;Painful Cervical Dystonia: Response to Treatment with Botulinum Toxin; Mov Disord1998;13(Suppl2):100.
Guyer, Barry M.;Mechanism of Botulinum Toxin in the Relief of Chronic Pain; Current Rev Pain1999;3(6):427-431.
Li, Yan, et al.;A Single Mutation in the Recombinant Light Chain of Tetanus Toxin Abolishes Its Proteolytic Activity and Removes the Toxicity Seen after Reconstitution with Native Heavy Chain; Biochemistry1994. 33, 7014-7020.
Schantz, Edward J., et al.;Properties and Use of Botulinum Toxin and Other Microbial Neurotoxins in Medicine; MicrobioIogical ReviewsMar. 1992, pp. 80-99, vol. 56, No. 1.
Tarsy, Daniel, et al.;Painful Cervical Dystonia: Clinical Features and Response to Treatment With Botulinum Toxin; Mov Disord1999; 14(6):1043-1045.
Zhou, Liqing, et al.;Expression and Purification of the Light Chain of Botulinum Neurotoxin A: A Single Mutation Abolishes Its Cleavage of SNAP-25 and Neurotoxicity after Reconstitution with the Heavy Chain; Biochemistry1995, 34, 15175-15181.
Guyer. B. ,Mechanism of botulinum toxin an the relief of chronic pain.Current Review of Pain, 1999, 3:427-431, XP-001031379.
Carruthers. A., et al.,Improvement of tension-type headache when treating wrinkles with botulinum toxin A infections, Headache, Oct. 1999:39:662-665, XP-001031356.
Diaz, J., et al.,Management of post-thoracotomy pseudoangina and myofascial pain with botulinum toxin, Anesthesioiogy, V 91, No. 3, Sep. 1999, pp. 877-879, XP-001031347.
Silberstein, S., et al.,Botulinum toxin type A as a migraine preventive treatment, Headache 2000:40:445-450, XP-002182692.
Gobel, H., et al.,Evidence-based medicine: botulinum toxin A in migraine and tension-type headache, Journal of Neurology. 2001 248 Supp 1: I/34-I/38, XP-002182693.
Dixon, W. J.;Efficient Analysis of Experimental Observations; Ann. Rev. Pharmacol. Toxicol.(1980); 20:441-462.
Dubuisson, D., et al.;The Formalin Test: A Quantitative Study of the Analgesic Effects of Morphine, Meperidine, and Brain Stem Stimulation in Rats and Cats; Pain(1977); 4:161-174.
Duc, C., et al.;Ultrastructural Localization of SNAP-25 Within the Rat Spinal Cord and Peripheral Nervous System; The Journal of Comparative Neurology(1995); 356:152-163.
Fauci, A.S., et al. (Editors);Harrison's Principles of Internal Medicine, 14thEdition (1998); McGraw-Hill; 2064-2065.
Garner, C.G., et al.;Time Course of Distant Effects of Local Injections of Botulinum Toxin; Movement Disorders; vol. 8, No. 1; 1993.
Habermann, E.;Inhibition by Tetanus and Botulinum A Toxin of the Release of(3H)noradrenaline and(3H)GABA from Rat Brain Homogenate; Exnerientia44(1988); 224-226.
Habermann, E.;I-Labeled Neurotoxin from Clostridium Botulinum A: Preparation, Binding to Synaptosomes and Ascent to the Spinal Cord; Naunyn Schrniedeberg's Arch. Pharmacol.; 281, 47-56 (1974).
Habermann, E., et al.;Tetanus Toxin and Botulinum A and C Neurotoxins Inhibit Noradrenaline Release from Cultured Mouse Brain; Journal of Neurochemistry; vol.51; No. 2 (1988); 522-527.
Hagenah, R., et al.;Effects of Type A Botulinum Toxin on the Cholinergic Transmission at Spinal Renshaw Cells and on the Inhibitoty Action at Ia Inhibitory Interneurones; Naunyn-Schmiedeberg's Arch. Pharmacol.; 299, 267-272 (1977).
Halpern, J.L., et al.;Neurospecific Binding, lnternalization, and Retrograde Axonal Transport; Current Topics in Microbiology and Immunology (1995) 195, pp. 221-41.
Johnson, B., et al.;Biomedical Aspects of Botulinum Toxin; J. Toxicol.-Toxin Reviews; Feb. 18, 1999; 18(1):1-l5.
Jung, H. H., et al.;Expression of Neurotransmitter Genes in Rat Spinal Motoneurons After Chemodenervation with Botulinum Toxin; Neuroscience(1997); vol. 78, No. 2; 469-479.
Kim, S. H., et al.;An Experimental Model for Peripheral Neuropathy Produced by Segmental Spinal Nerve Ligation in the Rat; Pain, 50 (1992); 355-363.
Li et al.;Biochemistry; 33:7014-7020 (1994).
Mochiida, S., et al.; Impairment of Syntaxin by Botulinum Neurotoxin C1 or Antibodies Inhibits Acetycholine Release but not Ca2+Channel Activity; Neuroscience(1995); vol. 65; No. 3; 905-915.
Naumann, et al.;Botulinum Toxin Type A in the Treatment of Focal, Axillary and Palmar Hyperhidrosis and Other Hyperhidrotic Conditions; European Journal of Neurology, 1999; vol. 6(suppl4):S3-S10 and S111-S115.
Nelson, P.G., et al.;Mouse Spinal Cord in Cell Culture. IV. Modulation of Inhibitory Synaptic Function; Journal of Neurophysiology; vol. 40, No. 5; Sep. 1977; 1178-1187.
Osen-Sand, A., et al.;Inhibition of Axonal Growth by SNAP-25 Antisense Oligonucleotides in vitro and in vivo; Nature; Jul. 29, 1993; vol. 364; 445-448.
Pearce, L. B., et al.;Pharmacologic Characterization of Botulinum Toxin for Basic Science and Medicine; Toxicon(1997); vol. 35, No. 9; 1373-1412.
Ragona, et al.;Management of Parotid Sialocele with Botulinum Toxin; Laryngoscope, 109:Aug. 1999; p. 1344-36.
Ransom, B.R., et al.;Mouse Spinal Cord in Cell Culture. I. Morphology and Intrinsic Neuronal Electrophysiologic Properties; Journal of Neurophysiology; vol. 40, No. 5; Sep. 1977; 1132-1150.
Ransom, B.R., et al.;Mouse Spinal Cord in Cell Culture. II. Synaptic Activity and Circuit Behavior, Journal of Neurophysiology; vol. 40, No. 5; Sep. 1977; 1151-1162.
Ransom, B.R., et al.;Mouse Spinal Cord in Cell Culture. III. Neuronal Chemosensitivity and its Relationship to Synaptic Activity; Journal of Neurophysiology; vol. 40, No. 5; Sep. 1977; 1163-1177.
Rees, H., et al.;Do Dorsal Root Reflexes Augment Peripheral Inflammation?; Neuro Report; vol. 5, No. 7; Mar. 21, 1994; 821-824.
Sanchez-Prieto, J., et al.;Botulinum Toxin A Blocks Glutamate Exocytosis from Guinea-Pig Cerebral Cortical Synaptosomes; Eur. J. Biochem. (1987); 165:675-681.
Shantz, E.J., et al.;Properties and Use of Botulinum Toxin and Other Microbial Neurotoxins in Medicine; Microbiol Rev.; 56:80-99 (1999).
Simpson, L.;Botulinum Toxin: Potent Poison, Potent Medicine; Hospital Practice; Apr. 15, 1999; 34(4):87-91.
Singh, B.R.;Critical Aspects of Bacterial Protein Toxins; Natural Toxins II(1996); Plenum Press, New York; pp. 63-84.
Tonra, J. R., et al.;Axotomy Upregulates the Anterograde Transport and Expression of Brain-Derived Neurotrophic Factor by Sensory Neurons; The Journal of Neuroscience; Jun. 1, 1998; 18(11):4374-4383.
Tsuda, M., et al.;In vivo Pathway of Thermal Hyperalgesia by Intrathecal Administration of α,β-methylene ATP in Mouse Spinal Cord: Involvement of the Glutamare-NMDA Receptor Sys

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Pain treatment by peripheral administration of a neurotoxin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pain treatment by peripheral administration of a neurotoxin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pain treatment by peripheral administration of a neurotoxin will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3430354

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.