PAI-2 conjugates for the treatment and imaging of cancer

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S001000, C514S019300, C514S019400, C514S019500, C514S019800, C424S001110, C424S009100, C424S009200

Reexamination Certificate

active

07998934

ABSTRACT:
A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises PAI-2 or a functional derivative, homologue, analogue, chemical equivalent or mimetic thereof, which PAI-2 is bound, linked, or otherwise associated with a toxin or label.

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