Liquid purification or separation – With means to add treating material – Chromatography
Patent
1993-08-13
1996-10-01
Therkorn, Ernest G.
Liquid purification or separation
With means to add treating material
Chromatography
2105021, 210656, 423308, 423311, 502400, B01D 1508
Patent
active
RE0353400
ABSTRACT:
Column packing materials useful in applications such as liquid chromatography, as well as a process for producing such a packing material are described. A first aspect of the invention concerns a column packing material composed of a spherical substrate having a coating of a calcium phosphate based compound on the surface thereof.
A second aspect of the invention concerns a packing material comprising porous calcium phosphate based granules having open pores with an average pore size of from 0.01 to 20 .mu.m, said granules being composed of crystalline particles with an average size of from 0.1 to 10 .mu.m.
A third aspect of the invention concerns a spherical packing material for liquid chromatography comprising spherical particles of at least one material selected from the group consisting of Ca.sub.10 (PO.sub.4).sub.6 (OH).sub.2, Ca.sub.3 (PO.sub.4).sub.2, Ca.sub.2 P.sub.2 O.sub.7, Ca(PO.sub.3).sub.2, Ca.sub.10 (PO.sub.4).sub.6 F.sub.2 and Ca.sub.10 (PO.sub.4).sub.6 Cl.sub.2, said packing material having a dense structure with a porosity of no more than 5%.
A fourth aspect of the invention concerns a packing for liquid chromatography comprising particles having at least on the surface thereof a fluoroapatite represented by formula (I):
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Ichitsuka Takeshi
Kawamura Katsumi
Ogawa Tetsuro
Sumita Masaya
Yokoo Akihiko
Asahi Kogaku Kogyo K.K.
Therkorn Ernest G.
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