Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Reexamination Certificate
2006-09-12
2006-09-12
Priebe, Scott D. (Department: 1633)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
C435S091400, C435S320100, C435S455000, C435S456000, C536S023720
Reexamination Certificate
active
07105346
ABSTRACT:
Presented are ways to address the problem of replication competent adenovirus in adenoviral production for use with, for example, gene therapy. Packaging cells having no overlapping sequences with a selected vector are suited for large scale production of recombinant adenoviruses. A system for use with the invention produces replication defective adenovirus. The system includes a primary cell containing a nucleic acid based on or derived from adenovirus and an isolated recombinant nucleic acid molecule for transfer into the primary cell. The isolated recombinant nucleic acid molecule is based on or derived from an adenovirus, has at least one functional encapsidation signal and at least one functional Inverted Terminal Repeat, and lacks overlapping sequences with the nucleic acid of the cell. Otherwise, the overlapping sequences would enable homologous recombination leading to replication competent adenovirus in the primary cell into which the isolated recombinant nucleic acid molecule is to be transferred.
REFERENCES:
patent: 4405712 (1983-09-01), Vande Woude et al.
patent: 4487829 (1984-12-01), Sharp et al.
patent: 4497796 (1985-02-01), Salser et al.
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4593002 (1986-06-01), Dulbecco
patent: 4727028 (1988-02-01), Santerre et al.
patent: 4740463 (1988-04-01), Weinberg et al.
patent: 4792525 (1988-12-01), Ruoslahti et al.
patent: 4797368 (1989-01-01), Carter et al.
patent: 4956281 (1990-09-01), Wallner et al.
patent: 5024939 (1991-06-01), Gorman
patent: 5096815 (1992-03-01), Ladner et al.
patent: 5166320 (1992-11-01), Wu et al.
patent: 5190931 (1993-03-01), Inouye
patent: 5198346 (1993-03-01), Ladner et al.
patent: 5204445 (1993-04-01), Plow et al.
patent: 5208149 (1993-05-01), Inouye
patent: 5223394 (1993-06-01), Wallner
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5240846 (1993-08-01), Collins et al.
patent: 5246921 (1993-09-01), Reddy et al.
patent: 5332567 (1994-07-01), Goldenberg
patent: 5349053 (1994-09-01), Landolfi
patent: 5378618 (1995-01-01), Sternberg et al.
patent: 5403484 (1995-04-01), Ladner et al.
patent: 5436146 (1995-07-01), Shenk et al.
patent: 5443953 (1995-08-01), Hansen et al.
patent: 5474935 (1995-12-01), Chatterjee et al.
patent: 5518913 (1996-05-01), Massie et al.
patent: 5521291 (1996-05-01), Curiel et al.
patent: 5534423 (1996-07-01), Palsson et al.
patent: 5543328 (1996-08-01), McClelland et al.
patent: 5545522 (1996-08-01), Van Gelder et al.
patent: 5547932 (1996-08-01), Curiel et al.
patent: 5552311 (1996-09-01), Sorscher et al.
patent: 5559099 (1996-09-01), Wickham et al.
patent: 5571698 (1996-11-01), Ladner et al.
patent: 5622699 (1997-04-01), Ruoslahti et al.
patent: 5652224 (1997-07-01), Wilson et al.
patent: 5670488 (1997-09-01), Gregory et al.
patent: 5707618 (1998-01-01), Armentano et al.
patent: 5712136 (1998-01-01), Wickham et al.
patent: 5731190 (1998-03-01), Wickham et al.
patent: 5753500 (1998-05-01), Shenk et al.
patent: 5756086 (1998-05-01), McClelland et al.
patent: 5770442 (1998-06-01), Wickham et al.
patent: 5824544 (1998-10-01), Armentano et al.
patent: 5837511 (1998-11-01), Falck-Pedersen et al.
patent: 5846782 (1998-12-01), Wickham et al.
patent: 5849561 (1998-12-01), Falck-Pedersen
patent: 5851806 (1998-12-01), Kovesdi et al.
patent: 5856152 (1999-01-01), Wilson et al.
patent: 5871727 (1999-02-01), Curiel
patent: 5871982 (1999-02-01), Wilson et al.
patent: 5877011 (1999-03-01), Armentano et al.
patent: 5891690 (1999-04-01), Massie
patent: 5919676 (1999-07-01), Graham et al.
patent: 5922315 (1999-07-01), Roy
patent: 5994106 (1999-11-01), Kovesdi et al.
patent: 5994128 (1999-11-01), Fallaux et al.
patent: 6007806 (1999-12-01), Lathe et al.
patent: 6033908 (2000-03-01), Bout et al.
patent: 6040174 (2000-03-01), Imler et al.
patent: 6051430 (2000-04-01), Plasterk et al.
patent: 6057155 (2000-05-01), Wickham et al.
patent: 6100086 (2000-08-01), Kaplan et al.
patent: 6127525 (2000-10-01), Crystal et al.
patent: 6140103 (2000-10-01), Einerhand et al.
patent: 6203975 (2001-03-01), Wilson et al.
patent: 6204052 (2001-03-01), Bout et al.
patent: 6210939 (2001-04-01), Gregory et al.
patent: 6232105 (2001-05-01), Einerhand et al.
patent: 6238893 (2001-05-01), Hoeben et al.
patent: 6265212 (2001-07-01), Fallaux et al.
patent: 6287857 (2001-09-01), O'riordan et al.
patent: 6306652 (2001-10-01), Fallaux et al.
patent: 6340595 (2002-01-01), Vogels et al.
patent: 6395519 (2002-05-01), Fallaux et al.
patent: 6413776 (2002-07-01), Vogels et al.
patent: 6447768 (2002-09-01), van Zonneveld et al.
patent: 6486133 (2002-11-01), Herlyn et al.
patent: 6492169 (2002-12-01), Vogels et al.
patent: 6602706 (2003-08-01), Fallaux et al.
patent: 6669942 (2003-12-01), Perricaudet et al.
patent: 6692966 (2004-02-01), Fallaux et al.
patent: 6855544 (2005-02-01), Hateboer et al.
patent: 6869794 (2005-03-01), Vogels et al.
patent: 6878549 (2005-04-01), Vogels et al.
patent: 2002/0102732 (2002-08-01), Fallaux et al.
patent: 2002/0164802 (2002-11-01), Fallaux et al.
patent: 2002/0173039 (2002-11-01), Fallaux et al.
patent: 2003/0104626 (2003-06-01), Fallaux et al.
patent: 2004/0087027 (2004-05-01), Gregory et al.
patent: A-28533/95 (1996-03-01), None
patent: 2053187 (1993-04-01), None
patent: 2117668 (1995-09-01), None
patent: 117060 (1984-08-01), None
patent: 95201611.1 (1995-06-01), None
patent: 95201728.3 (1995-06-01), None
patent: 1016726 (1998-12-01), None
patent: 1067188 (1999-07-01), None
patent: 1020529 (1999-11-01), None
patent: WO 91/00360 (1991-01-01), None
patent: WO 91/05805 (1991-05-01), None
patent: WO 91/05871 (1991-05-01), None
patent: WO 92/02553 (1992-02-01), None
patent: WO 92/13081 (1992-08-01), None
patent: WO 93/03769 (1993-03-01), None
patent: WO 93/06223 (1993-04-01), None
patent: WO 93/07282 (1993-04-01), None
patent: WO 93/07283 (1993-04-01), None
patent: WO 94/08026 (1994-04-01), None
patent: WO 94/10323 (1994-05-01), None
patent: WO 94/11506 (1994-05-01), None
patent: WO 94/12649 (1994-06-01), None
patent: WO 94/15644 (1994-07-01), None
patent: WO 94/17832 (1994-08-01), None
patent: WO 94/23582 (1994-10-01), None
patent: WO 94/24297 (1994-10-01), None
patent: WO 94/24299 (1994-10-01), None
patent: WO 94/26914 (1994-11-01), None
patent: WO 94/26915 (1994-11-01), None
patent: WO 94/28152 (1994-12-01), None
patent: WO 94/28938 (1994-12-01), None
patent: WO 95/00655 (1995-01-01), None
patent: WO 95/02697 (1995-01-01), None
patent: WO 95/05201 (1995-02-01), None
patent: WO 95/06745 (1995-03-01), None
patent: WO 95/14785 (1995-06-01), None
patent: WO 95/16037 (1995-06-01), None
patent: WO 95/16772 (1995-06-01), None
patent: WO 95/21259 (1995-08-01), None
patent: WO 95/26411 (1995-10-01), None
patent: WO 95/26412 (1995-10-01), None
patent: WO 95/27071 (1995-10-01), None
patent: WO 95/31187 (1995-11-01), None
patent: WO 95/31566 (1995-11-01), None
patent: WO 95/34671 (1995-12-01), None
patent: WO 96/00790 (1996-01-01), None
patent: WO 96/07739 (1996-03-01), None
patent: WO 96/00326 (1996-04-01), None
patent: WO 96/10087 (1996-04-01), None
patent: WO 96/12030 (1996-04-01), None
patent: WO 96/13596 (1996-05-01), None
patent: WO 96/13597 (1996-05-01), None
patent: WO 96/13598 (1996-05-01), None
patent: WO 96/14061 (1996-05-01), None
patent: WO 96/14837 (1996-05-01), None
patent: WO 96/16676 (1996-06-01), None
patent: WO 96/17073 (1996-06-01), None
patent: WO 96/18418 (1996-06-01), None
patent: WO 96/18740 (1996-06-01), None
patent: WO 96/24453 (1996-08-01), None
patent: WO 96/26281 (1996-08-01), None
patent: WO 96/33280 (1996-10-01), None
patent: WO 96/35798 (1996-11-01), None
patent: WO 96/40955 (1996-12-01), None
patent: WO 97/00326 (1997-01-01), None
patent: WO 97/00947 (1997-01-01), None
patent: WO 97/04119 (1997-02-01), None
patent: WO 97/05255 (1997-02-01), None
patent: WO 97/12986 (1997-04-01), None
patent: WO 97/20575 (1997-06-01), None
patent: WO 97/38723 (1997-10-01), None
patent: WO 98/07865 (1998-02-01), None
patent: WO 98/11221 (1998-03-01), None
patent: WO 98/13499 (1998-04-01),
Bout Abraham
Fallaux Frits J.
Hoeben Robert C.
Valerio Domenico
van der Eb Alex Jan
Crucell Holland B.V.
Priebe Scott D.
TraskBritt
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