Packaging cells comprising codon-optimized gagpol sequences...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Reexamination Certificate

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C435S320100, C435S235100, C435S456000, C435S465000, C424S093100, C424S093200, C424S093210, C424S093600

Reexamination Certificate

active

06958226

ABSTRACT:
Novel packaging cell lines useful for generating viral accessory protein independent HIV-derived retroviral vector particles, methods of constructing such packaging cell lines and methods of using the viral accessory protein independent HIV-derived retroviral vector particles are disclosed.

REFERENCES:
patent: WO 94/19478 (1994-09-01), None
patent: WO 94/29438 (1994-12-01), None
patent: WO 97/22709 (1997-06-01), None
patent: WO 97/27310 (1997-07-01), None
patent: WO 98/12207 (1998-03-01), None
patent: WO 98/17815 (1998-04-01), None
patent: WO 98/17816 (1998-04-01), None
patent: WO 00/31280 (2000-06-01), None
Kotsopoulou, et al. Journal of Virology, May 2000, vol. 74, No. 10, pp. 4839-4952.
Paul Luciw, Fundamental Virology, 3rd Ed., Fields, Knipe and Howley editors-in-chief, Lippencott-Raven, Philadelphia-New York, 1996, Chapter 27, p. 850.
Srinivasakumar, N. et al., “The Effect of Viral Regulatory Protein Expression on Gene Delivery by Human Immunodeficiency Virus Type 1 Vectors Produced in Stable packaging Cell Lines,”Journal of Virology, 71(8) :5841-5848 (1997).
Haselhorst, D. et al., “Stable Packaging Cell Lines and HIV-1 Based Retroviral Vector Systems,”Gene Therapy,1 (Suppl. 2) :S14 (Nov. 18, 1994).
St. Louis, D. et al., “Construction and Characterization of HIV-1 Retroviral Vectors and Replication-Defective HIV-1 Packaging Cell Lines,”International Conference on AIDS and the STD World Congress,p. 244 (Jun. 1, 1993).
Carroll, R. et al., “A Human Immunodeficiency Virus Type 1 (HIV-1)—Based Retroviral Vector System Utilizing Stable HIV-1 Packaging Cell Lines,”J. of Virology,68 (9) : 6047-6051 (Sep. 1, 1994).
Holler, T.P. et al., “HIV1 Integrase Expressed inEscherichia colifrom a Synthetic Gene,”Gene,136 : 323-328 (Dec. 22, 1993).
André, S. et al., “Increased Immune Response Elicited by DNA Vaccination with a Synthetic GP120 Sequence with Optimized Codon Usage,”J. of Virology,72 (2) : 1497-1503 (Feb. 1, 1998).
Naldini, L. et al., “In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector,”Science,272:263-267 (Apr. 12, 1996).
Soneoka, Y. et al., “A transient three-plasmid expression system for the production of high titer retroviral vectors,”Nucleic Acids Research,23 (4):628-633 (1995).
Kim, V.N. et al., “Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus type 1,”J. of Virology,72 (1):811-816 (Jan. 1998).
Srinivasakumar, N. et al., “The Effect of Viral Regulatory Protein Expression on Gene Delivery by Human Immundeficiency Virus Type 1 Vectors Produced in Stable Packaging Cell Lines,”J. of Virology,71(8):5841-5848 (Aug. 1997).
Haas, J. et al., “Codon usage limitation in the expression of HIV-1 envelope glycoprotein,”Current Biology,6(3):315-324 (1996).
Schwartz, S. et al., “Mutational Inactivation of an Inhibitory Sequence in Human Immunodeficiency Virus Type 1 Results in Rev-IndependentgagExpression,”J. Virology,66(12):7176-7182 (Dec. 1992).
Markowitz, D. et al., “A Safe Packaging Line for Gene Transfer: Separating Viral Genes on Two Different Plasmids,”J. of Virology,62:1120-1124 (Apr. 1988).
Dougherty, J.P. et al., “New Retrovirus Helper Cells with Almost No Nucletide Sequence Homology to Retrovirus Vectors,”J. of Virology,63(7):3209-3212 (Jul. 1989).
Miller, A.D and Buttimore, C., “Redesign of Retrovirus Packaging Cell Lines to Avoid Recombination Leading to Helper Virus Production,”Molecular and Cellular Biology,6(8):2895-2902 (Aug. 1986).
Mann, R. et al., “Construction of a Retrovirus Packaging Mutant and Its Use to Produce Helper-Free Defective Retrovirus,”Cell,33:153-159 (May 1983).
Cone, R.D. and Mulligan, R.C., “High-efficiency gene transfer into mammalian cells: Generation of helper-free recombinant with broad mammalian host range,” Proc. Natl. Acad. Sci. USA, 81:6349-6353 (Oct. 1984).
Danos, O. and Mulligan, R.C., “Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges,”Proc. Natl. Acad. Sci. USA,85:6460-6464 (Sep. 1988).
Markowitz, D.G. et al., “Safe and Efficient Ecotropic and Amphotropic Packaging Lines for Use in Gene Transfer Experiments,”Trans. Assoc. Am. Physicians,101:212-218 (1988).
Fleischman, R.A., “Southwestern Internal Medicine Conference: Human Gene Therapy,”The American Journal of the Medical Sciences,301(5):353-363 (May 1991).
Parveen, Z., et al., “Spleen Necrosis Virus-Deprived C-type Retroviral Vectors for Gene Transfer to Quicscent Cells, ”Nature Biotechnology18:623-629 (2000).

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