Packaged stable enema solution or suspension containing 5-aminos

Details Packaged stable enema solution or suspension containing 5-aminos Packaged stable enema solution or suspension containing 5-aminos

1989-05-12

1990-06-26

Foster, Jimmy G.

Special receptacle or package

Including ancillary article contacting medium

Gas medium

514166, B65D 8124

Patent

active

RE0332399

ABSTRACT:
A packaged enema solution or suspension consisting essentially of an effective amount of 5-ASA or a pharmaceutically acceptable salt or ester thereof, a chelating agent, in antioxidant and a buffer, the solution or suspension having a pH value of from 4 to 7 and being contained in a plastic bottle under an inert gas, the plastic bottle being packaged in a diffusion-tight light-impervious package in the same inert gas as is present in the bottle.

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Binder, V. et al., "Topical 5-Aminosalicyclic Acid Versus Prednisolone in Ulcerative Proctosigmoiditis", Digestive Diseases & Sciences, Oct. 3, 1985.
Willoughby, C. et al, "5-Aminosalicyclic Acid (Pentasa) in Enema Form for the Treatment of Active Ulcerative Colitis", Ital. J. Gastoenterol., 1986; 18: 15-17.
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