Packaged pharmaceutical product

Special receptacle or package – For body treatment article or material – With gas permeable cover

Patent

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Details

206471, B65D 6538

Patent

active

050525581

ABSTRACT:
A method of filling, sealing and sterilizing a pharmaceutical package including a polypropylene bottle containing a balanced salt solution includes the steps of filling each bottle to maximum capacity to exclude residual air, the introduction of a silicone rubber gasket into the bottle cap to absorb pressure and prevent leakage during a steam sterilization procedure, and the enclosure of the filled bottles in a blister pack before steam sterilizing. The blister packs have Tyvek.TM. lids and are placed blister-side-up during the sterilization process to eliminate deformation of the blister during sterilization. Maximum filling of the bottle with liquid and the substantial elimination of air prevents dimpling of the bottle.

REFERENCES:
patent: 2004079 (1935-06-01), McManus
patent: 3032182 (1962-05-01), Bechtold
patent: 3926311 (1975-12-01), Laske
patent: 4150744 (1979-04-01), Fennimore
patent: 4467588 (1984-08-01), Carveth
patent: 4482053 (1984-11-01), Alpern et al.
patent: 4805377 (1989-02-01), Carter
patent: 4962856 (1990-10-01), Carter

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