P53 dependent apoptosis-associated gene and protein

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C536S023500, C536S023100, C435S252300, C435S254110, C435S254200, C435S320100, C435S325000, C435S419000, C435S069100, C435S070100, C435S071100, C435S004000, C530S300000, C530S350000, C530S395000

Reexamination Certificate

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07569351

ABSTRACT:
A novel apoptosis-associated gene p53AIPI is isolated by screening for a gene the expression of which is induced by p53. Since the protein encoded by this gene has an activity of inducing apoptosis, this gene is useful in developing effective therapeutic agents for cancer mediated by apoptosis. A method of screening for a compound controlling the induction of apoptosis which is expected as being useful in developing an apoptosis controlling agent.

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