P53 binding protein-related protein in cardiomyopathy

Details P53 binding protein-related protein in cardiomyopathy P53 binding protein-related protein in cardiomyopathy

2006-04-25

2006-04-25

Chan, Christina (Department: 1644)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S455000, C435S252300, C435S320100, C536S023100

Reexamination Certificate

active

07033793

ABSTRACT:
The present invention is directed to a mouse model of dilated cardiomyopathy in which animals are deficient in the expression of a gene encoding a p53 binding protein-related protein (PRP). The invention also encompasses the mouse PRP gene and protein themselves as well as counterparts found in the human. The various genes and proteins can be used in making transgenic animals and in assays designed to determine the likelihood of an individual developing cardiomyopathy.

REFERENCES:
patent: WO 00/32628 (2000-06-01), None
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Abstract of AF1 above.
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