P53-binding polypeptides and polynucleotides encoding same

Details P53-binding polypeptides and polynucleotides encoding same P53-binding polypeptides and polynucleotides encoding same

1995-03-02

1998-05-26

Walsh, Stephen

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

536 235, 435 691, C07K 1447, C12N 1512, C12N 1564

Patent

active

057566690

ABSTRACT:
The invention provides mammalian polypeptides which bind wild-type and/or mutant mamalian p53 proteins, polynucleotides encoding such polypeptides, screening assays for drug development employing such polypeptides and polynucleotides, immunological and other reagents for diagnostic, therapeutic, and research applications.

REFERENCES:
Iwabuchi, K et al. Proc. Natl. Acad. Sci USA vol 91 pp. 6098-6102 Jun., 1994.

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