Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-01-10
1998-12-01
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 4351723, 435 691, 4353201, 4352402, 4352523, 4352542, 435 71, 435 72, 435 79, C12Q 168, C12P 1934, C12N 1570, C07H 2102
Patent
active
058436480
ABSTRACT:
The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated p15. This invention further relates to bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess or prognoses a mammal afflicted with melanoma or metastata melanoma. This invention also provides immunogenic peptides derived from the p15 melanoma antigen and a second melanoma antigen designated tyrosinase. The proteins and peptides provided can serve as an immunogen or vaccine to prevent or treat melanoma.
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Robbins Paul F.
Rosenberg Steven A.
Jones W. Gary
Rees Dianne
The United States of America as represented by the Secretary, De
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