P-(trifluoromethylquinolylamino)benzamides, pharmaceutical dosag

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260287AR, 424258, 260268BQ, A61K 3147, C07D21544

Patent

active

040256294

ABSTRACT:
Novel p-(trifluoromethylquinolylamino)benzamides are provided, for example, p-[(7-trifluoromethyl-4-quinolyl)-amino]-N,N-(3-methyl-3-azapentamethylene )benzamide and 1-[p-[[7-(trifluoromethyl)-4-quinolyl]amino]benzoyl]piperazine dihydrochloride. Also provided are pharmaceutical dosage unit forms for systemic administration and methods for their systemic administration. The compound, dosage unit forms and methods of systemic administration are useful in obtaining antihypertensive and anti-anxiety effects in mammals.

REFERENCES:
patent: 2940974 (1960-06-01), Surrey
patent: 3632761 (1972-01-01), Graham et al.
Fukami, Amides of 4-Quinolylamino Acid as Chemotherapeutic Agents, Thesis, (1967), p. 8.

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