P-(substituted and unsubstituted-phenyl)-1-phenyl-2,3-butadien-1

Details P-(substituted and unsubstituted-phenyl)-1-phenyl-2,3-butadien-1 P-(substituted and unsubstituted-phenyl)-1-phenyl-2,3-butadien-1

1977-02-17

1978-07-11

Thomas, Jr., James O.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31045, C07C 4320

Patent

active

041003004

ABSTRACT:
Disclosed are compounds of the class 1-phenyl-2,3-butadien-1-ol e.g. 2-(p-biphenyl)-3,4-pentadien-2-ol, which are useful by reason of their pharmacological activity in animals, e.g., as anti-inflammatory agents and tranquilizers. Said compounds can be prepared, e.g., by reduction of a corresponding 4-substituted-1-phenyl-2-butyne-1-ol with a complex hydride such as lithium aluminum hydride.

REFERENCES:
patent: 3859256 (1975-01-01), Teufel et al.
patent: 3888933 (1975-06-01), Anderson
patent: 3929902 (1975-12-01), Galantay
patent: 3969418 (1976-07-01), Teufel et al.
patent: 4032580 (1977-06-01), Galantay

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