P-Glyoxyloylphenylalkanoic acid bis(thiosemicarbazone) derivativ

Details P-Glyoxyloylphenylalkanoic acid bis(thiosemicarbazone) derivativ P-Glyoxyloylphenylalkanoic acid bis(thiosemicarbazone) derivativ

1983-10-07

1985-12-17

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 564 20, A61K 4900, A61K 4300

Patent

active

045592217

ABSTRACT:
A radioactive diagnostic agent which comprises a physiologically active substance and a radioactive metallic element combined with a compound of the formula: ##STR1## wherein R is a hydrogen atom or a C.sub.1 -C.sub.3 alkyl group and n is an integer of 0 to 4. The agent is characteristic in having a high stability even after being administered into a human body and showing the substantially the same behavior as the physiologically active substance itself in a human body.

REFERENCES:
patent: 3382275 (1968-05-01), Barrett
patent: 3709935 (1973-01-01), Barrett
patent: 3824276 (1974-07-01), Murray et al.
patent: 4287362 (1981-09-01), Yokoyama et al.
patent: 4338248 (1982-07-01), Yokoyama et al.
Japanese Journal of Nuclear Medicine, vol. 19, No. 9, p. 1336, issued Oct. 20, 1982 (with translation).
Yokoyama et al, Chem. Abstracts, 101, (1984), #35249u.
Yokoyama et al, Chem. Abstracts, 85, (1976), #139238g.

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