P-Glu-Trp-Ser-Tyr-D-Lys-Leu-Arg-Pro-Gly-NH.sub.2 and intermediat

Details P-Glu-Trp-Ser-Tyr-D-Lys-Leu-Arg-Pro-Gly-NH.sub.2 and intermediat P-Glu-Trp-Ser-Tyr-D-Lys-Leu-Arg-Pro-Gly-NH.sub.2 and intermediat

1974-11-04

1976-02-10

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

039376958

ABSTRACT:
D-Lys.sup.6 -des-His.sup.2 -LRF, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. The novel nonapeptide exhibits anti-ovulatory activity in mammals.

REFERENCES:
patent: 3842065 (1974-10-01), Rees
patent: 3855199 (1974-12-01), Foell et al.
Fujino et al.: Biochem. Biophys. Res. Comm., 57, 1248-1256 (1974).

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