P-aminophenol derivatives, and processes for production of and u

Details P-aminophenol derivatives, and processes for production of and u P-aminophenol derivatives, and processes for production of and u

1992-02-27

1993-02-16

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544336, 544407, 544408, 544409, A61K 31495, C07D24100, C07D24102, C07D24104

Patent

active

051871610

ABSTRACT:
A p-aminophenol derivative having anti-inflammatory activity, represented by the formula ##STR1## wherein each of R.sup.1 and R.sup.2 is independently a hydrogen atom or a C.sub.1-6 acyl group; Ar is a pyrazine, pyrazine N-oxide, thiazole, benzene, pyridine, pyridazine, pyrimidine or triazine ring; R.sup.3 is a hydrogen atom, a C.sub.1-6 alkyl group, a C.sub.1-6 alkoxy-carbonyl-C.sub.1-6 alkyl group, a C.sub.1-6 alkoxy group, a halogen atom or a carboxy-C.sub.1-6 alkyl group; A is a C.sub.1-6 alkylene group; and B is a C.sub.1-6 alkyl group, or a salt thereof.

REFERENCES:
patent: 4868183 (1989-09-01), Kanai et al.
patent: 4906662 (1990-03-01), Hashimoto et al.
Derwent abstract for Japanese Unexamined Patent Publication 60-258,173, published Dec. 20, 1985.
Derwent abstract for Japanese Unexamined Patent Publication 62-123,180, published Jun. 4, 1987.
Derwent abstract for Japanese Unexamined Patent Publication 62-087,860, published Apr. 22, 1987.
Derwent abstract for Japanese Unexamined Patent Publication 63-115,860, published May 20, 1988.

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