Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-29
1998-12-08
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 701, 435 703, 4351723, 4352402, 4352523, 43525411, 536 231, 536 235, 536 253, 935 52, C07H 2100
Patent
active
058467661
ABSTRACT:
The present invention relates to a receptor for a posterior pituitary hormone, oxytocin; a DNA sequence encoding for the receptor; a recombinant DNA molecule containing the DNA sequence and a transformant comprising the recombinant DNA molecule. The present invention further relates to methods of detection and diagnosis and a kit to aid in same which comprise either oxytocin, its receptor or antibodies to the receptor.
REFERENCES:
patent: 5466584 (1995-11-01), Tanizawa et al.
Soloff, "Purification and characterization of oxytocin receptors from rat mammary gland", Colloque Inserm 208:65-74 (1991).
Kimura et al, "Structure and expression of a human oxytocin receptor", Nature 356:526-529 (1992).
Soloff et al, "Solubilization and Properties of Oxytocin Receptors from Rat Mammary Gland", Endocrinology 120(6):2474-2482 (1987).
Soloff et al, "Determination of the Functional Size of Oxytocin Receptors in Plasma Membranes from Mammary Gland and Uterine Myometrium of the Rat by Radiation Inactivation", Endocrinology 122(5):1769-1772 (1988).
Azuma Chihiro
Kimura Tadashi
Okayama Hiroto
Saji Fumitaka
Tanizawa Osamu
Kile Bradford E.
Nucker Christine M.
Rohto Pharmaceutical Co. Ltd.
Scheiner Laurie
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