Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Oxytocin; vasopressin; related peptides
Patent
1993-04-26
1994-12-13
Hill, Jr., Robert J.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Oxytocin; vasopressin; related peptides
530317, 530328, 930260, 930DIG565, C07K 716
Patent
active
053730895
ABSTRACT:
A novel compound is disclosed for inhibiting the effects of oxytocin in a female mammal. As an analog of oxytocin the compound is named [(S)PMP.sup.1,D-Trp.sup.2,Pen.sup.6,Arg.sup.8 ] oxytocin. This compound can be administered to pregnant women to arrest premature labor while avoiding unwanted side effects due to antagonism of the antidiuretic hormone, vasopressin.
REFERENCES:
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Flouret George
Wilson Laird
Hill Jr. Robert J.
Northwestern University
Wessendorf T. D.
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