Oxysterol inhibition of dietary cholesterol uptake

Details Oxysterol inhibition of dietary cholesterol uptake Oxysterol inhibition of dietary cholesterol uptake

1997-06-19

1999-07-27

Jordan, Kimberly

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514824, A61K 3156

Patent

active

059290625

ABSTRACT:
A composition useful to inhibit cholesterol absorption from the diet is provided. The composition comprises a pharmaceutically acceptable combination of one or more oxysterols and a suitable carrier. The present oxysterol composition can be used therapeutically, prescribed to individuals who are required to reduce cholesterol intake. Alternatively, the composition can used as a dietary supplement by any individual desiring to moderate cholesterol intake.

REFERENCES:
patent: 5244887 (1993-09-01), Straub
patent: 5502045 (1996-03-01), Miettinen et al.
Folch et al., "A Simple Method for the Isolation and Purification of Total Lipides from Animal Tissues", J. Biol. Chem., 1957, 226, 497-509.
Kelley et al., "Effect of Pectin, Gum Arabic and Agar on Cholesterol Absorption, Synthesis, and Turnover in Rats", J. Nutrition, 1978, 108, 630-639.
CA 89:71635, Erickson et al, 1978.
CA 89:186088, Kitame et al, 1978.

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