Oxygenated alkyl substituted bicyclo alkanes

Details Oxygenated alkyl substituted bicyclo alkanes Oxygenated alkyl substituted bicyclo alkanes

1986-03-12

1987-08-25

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514691, 514729, A61K 3112, A61K 3122

Patent

active

046893458

ABSTRACT:
Anti-androgenic composition compound of the formula ##STR1## wherein Q is CO, CH(OR), CR(OH), or CR (OC)-lower alkyl);

REFERENCES:
patent: 4000174 (1976-12-01), Henrick et al.
patent: 4292432 (1981-09-01), Ono et al.
patent: 4322435 (1982-03-01), Kojima et al.
Ford et al., "Anti-Neoplastic Effects of Metcyclor".
Ford et al., "Modulation of Connective Tissue Metabolism by Steroid Hormones and Ethocyn".
King et al., "Effects of Cyoctol vs. 13-Cis Retinoic Acid on Dihydrotestosterone Receptor Binding in Human Facial Sebacious Glands".
Ford et al., "Dense Intraabdominal Adhesions-A Manifestation of Localized, Hyper-Androgen Receptors".
Ford et al., "Differential Androgen Receptor Activity in Patients with Androgenic alopecia and the Effects of Cyoctol on Dihydrotestosterone (DHT) Protein Binding".
King et al., "Effects of Cyoctol vs. 13-Cis Retinoic Acid on Dihydrotetosterone (DHT) Receptor Binding in Human Facial Skin Fibroblasts".
Hammill et al., "Effects of Cyoctol on the Hormonally Stimulated Increases in DNA and RNA Metabolism in Fungi".
Hammill et al., "Dihydrotestosterone and Estradiol Receptors in Trichomonas Vaginalis and the Effects of Cyoctol".
King et al., "Increased Androgen Binding in Keloids and its Inhibition with Cyoctol".
Selim et al., "Absorption, Tissue Distribution, Blood Level and Excretion of .sup.14 C Labeled Cyoctol Following Oral or Dermal Administration", Abstract presented at 6th CIRD Symposium, Cannes, France, Oct. 1985.

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