Oxygen, sulfur and nitrogen substituted cyclohexene and cyclohex

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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560 81, 560 85, 560107, 560194, 556440, C07C 6952, C07C 6964, C07C 6976, C07C 6984, C07C 6986

Patent

active

061662445

ABSTRACT:
Compounds of the Formula 1, Formula 2, Formula 3 and Formula 4 wherein the symbols have the meaning assigned to them in the disclosure have retinoid-like biological activity. ##STR1##

REFERENCES:
patent: 4391731 (1983-07-01), Boller et al.
patent: 4539154 (1985-09-01), Krebs
patent: 4739098 (1988-04-01), Chandraratna
patent: 4804670 (1989-02-01), Wuest et al.
patent: 4923884 (1990-05-01), Chandraratna
patent: 4927947 (1990-05-01), Chandraratna
patent: 5426118 (1995-06-01), Chandraratna et al.
patent: 5451605 (1995-09-01), Chandraratna et al.
patent: 5455265 (1995-10-01), Chandraratna
patent: 5470999 (1995-11-01), Chandraratna
patent: 5618836 (1997-04-01), Chandraratna et al.
patent: 5760276 (1998-06-01), Beard et al.
patent: 5877207 (1999-03-01), Klein et al.
Dawson and William H. Okamura, Chemistry and Biology of Synthetic Retinoids published by CRC Press, Inc., 1990, pp. 334-335.
Negishi et al., "Conversion of Methyl Ketones into Terminal Acetylenes and (E)-Trisubstituted Olefins of Terpenoid Origin", J. Org. Chem. 45 No. 12, 1980 p. 2526.
Verma & Boutwell, Cancer Research, (1977), 37 2196-2201.
Cancer Research: 1662-1670 (1975).
Feigner P. L. and Holm M. (1989) Focus, 112.
Heyman et al., Cell 68, 397-406, (1992).
Allegretto et al., J. Biol. Chem. 268, 26625-26633.
Mangelsdorf et al., The Retinoids: Biology, Chemistry and Medicine, pp. 319-349, Raven Press Ltd., New York.
Cheng et al., Biochemical Pharmacology vol. 22 pp. 3099-3108.
Klein et al., J. Biol. Chem. 271, 22692-22696 (1996).
Chen et al. (1987) Mol. Cell. Biol. 7, 2745-2752.
de Wet (1987) Mol. Cell. Biol. 7, 725-737.
Nagpal et al., EMBO J. 12, 2349-2360 (1993).
Corey, E. J., Schmidt, G., Tet. Lett., 399, (1979).
Omura, K., Swern D., Tetrahedron, 1978, 34, 1651.

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