Oxygen permeable membrane in fermenter for oxygen enrichment of

Details Oxygen permeable membrane in fermenter for oxygen enrichment of Oxygen permeable membrane in fermenter for oxygen enrichment of

1982-12-03

1987-03-10

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435241, 435284, 435286, 435315, 210220, 2103211, 2104332, 2104971, C12N 500, C12N 502, C12M 300, C12M 302, C12M 106, B01D 1300, B01D 2942, B01D 2948

Patent

active

046491147

ABSTRACT:
The growth of animal cells in a fermenter is promoted by enriching the liquid nutrient medium or broth with oxygen diffused into the liquid through a permeable membrane, such as one made of silicone rubber or polytetrafluoroethylene (Teflon). Superior cell growth in larger volumes is achieved by feeding in the oxygen in this way instead of bubbling it in.

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patent: 4537860 (1985-08-01), Tolbert et al.
Jakoby, W. B. & Pastan, I. H., "Cell Culture", Methods in Enzymology, vol. 58; Academic Press, 1979; pp. 450-455.

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