Surgery – Body protecting or restraining devices for patients or infants – Wound shields
Patent
1998-05-26
1999-12-14
Brown, Michael A.
Surgery
Body protecting or restraining devices for patients or infants
Wound shields
602 41, A61R 1300
Patent
active
060004037
DESCRIPTION:
BRIEF SUMMARY
The present invention relates to a topical hyperbaric bandage and to a method of wound healing utilising the same.
Hyperbaric apparatus for the treatment of open wounds and lesions by application thereto for therapeutic gas such as oxygen with or without a pharmacologically acceptable additive is generally known. For example in U.S. Pat. No. 5,154,697 and U.S. Pat. No. 4,801,291 there are described various arrangements for the treatment of open lesions in wounds in a hyperbaric chamber with oxygen which promotes granulation, raises capillary blood oxygen levels and elevates redox potential thereby suppressing bacterial growth and encouraging revascularisation.
In my earlier patent Application, WO94/21323 I have described a topical hyperbaric bandage comprising a gas diffusion resistant flexible and/or resilient sheet material including an adhesive layer to be fixed to the skin, said adhesive layer surrounding the treatment area, at least one release layer disposed over the adhesive layer and means for supplying a therapeutic gas to the treatment area, the device being adapted to retain a single charge of a therapeutic gas over a treatment period. The device may be further adapted such that it is rechargeable at least once with therapeutic gas for a repeat treatment whilst the device is in situ.
The advantage of arrangements of this type is that since previously hyperbaric treatment was only available in suitably equipped hospitals, the arrangement according to my earlier application allowed the translation of hyperbaric treatment to the domestic sphere. This is because not only were the hyperbaric devices small, but also the oxygen supply required was much smaller than had hitherto been the case.
Hyperbaric oxygen treatment has been somewhat controversial in the past because of the problems with oxygen toxaemia. We have found that relatively small super-atmospheric pressures of for example 1.03 to 1.04 atmospheres are effective to assist in revascularisation as long as the treatment does not go on too long. For example, treatments of many conditions, e.g. bedsores, for much longer than four hours at one time may well induce oxygen toxaemia and hence be counterproductive. Our previous invention was based on the proposition that only a single charge of oxygen was not only necessary but highly desirable. Although, the single charge may be repeated after a few days or even after a few hours if required. The previous practice of flowing oxygen over a lesion for an indeterminate period was not only unnecessary, but clinically counterproductive.
One attempt at producing such a bandage is to be found in GB-A-2024012. This reveals a two-part storable topical hyperbaric wound dressing which comprises a peroxy compound such as hydrogen peroxide and an agent for activating the same to produce oxygen. Both components are absorbed or disposed on juxtaposed sheets and rely on either moisture from the wound to achieve activation or from the crushing of microspheres of the initiator prior to assembly about the wound.
This arrangement is not satisfactory in part because the peroxy compounds are so labile when not liquid. Although they may be absorbed on a particular material experimentally, storage in commercial conditions results in the peroxy compound deteriorating rapidly. This is particularly so a higher temperatures.
What is required therefore is a hyperbaric bandage which is ready to use, easy to store and reliable. This is achieved in part by providing a liquid reservoir of the peroxy compound. A catalyst may not be required as such because haemoglobin from the wound may act as the necessary catalyst in some circumstances.
The present invention is characterised in that the topical hyperbaric bandage comprises a reservoir for a source of therapeutic gas in liquid form and in that gas release from the reservoir is initiable after the bandage has been secured to the skin. It will be appreciated that the therapeutic gas in non-gaseous form is most usually stored in chemical form and is released by a biologically acceptab
REFERENCES:
patent: 4699146 (1987-10-01), Sieverding
patent: 4909244 (1990-03-01), Quarfoot
patent: 5106629 (1992-04-01), Cartmell
patent: 5322695 (1994-06-01), Shah
Brown Michael A.
Lehrer Norman E.
LandOfFree
Oxygen bandage does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oxygen bandage, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxygen bandage will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-854711