Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1993-03-24
1994-07-05
Prescott, Arthur C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560221, 560223, 560225, 560250, 560251, 560255, 549 29, 549 74, 549 75, 549 76, 549 77, 546339, 546340, 546346, 574438, 574311, 574337, 574443, C07C 6700, A61K 3138, C07D30752
Patent
active
053269020
ABSTRACT:
Oxyalkyne compounds corresponding to the formula I ##STR1## in which the substituent Y in the meta- or para-position is R.sup.1 represents CH.sub.3 or NH.sub.2, R.sup.2 represents H or CH.sub.3, R.sup.3 represents H, C.sub.1-3 -alkyl or COCH.sub.3, and Ar represents an aromatic residue selected from the group ##STR2## with the proviso that the substituents R.sup.4, R.sup.5 and R.sup.6 are the same or different and each substituent represents H, F, Cl, Br, C.sub.1-6 -alkyl, CF.sub.3 or C.sub.1-6 -alkoxy, and R.sup.7 represents H, F, Cl, Br, C.sub.1-3 -alkyl or CF.sub.3,
in the form of their racemates or mixtures of diastereoisomers or in optically active form, which are suitable active ingredients in pharmaceutical compositions.
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Englberger Werner
Geist Cornelia
Haurand Michael
Seipp Ulrich
Vollenberg Werner
Gruenenthal GmbH
Prescott Arthur C.
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