Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-09-07
2000-10-31
Seaman, D. Margaret
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546159, 546160, A61K 314706, C07D21558, C07D21542
Patent
active
061403423
ABSTRACT:
Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
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Chemical Abstracts 123:55716, 1995.
Chemical Abstracts 116:151569, 1991.
Gordon DJ, et al., Circulation. 79(1):8-15, 1989 Jan., "High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies".
Goldstein Steven W.
Makowski Michael R.
Ruggeri Roger B.
Wester Ronald T.
Benson Gregg C.
Olson A. Dean
Pfizer Inc.
Richardson Peter C.
Seaman D. Margaret
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