Oxotremorine antagonists

Details Oxotremorine antagonists Oxotremorine antagonists

1974-05-24

1976-05-25

Winters, Sherman D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239B, 260239BF, 26029371, 26029386, 26029387, 26032643, 26032685, 424267, 424274, C07D29512, C07D20712

Patent

active

039593118

ABSTRACT:
A new class of amino-imide compounds is disclosed in which a 2-oxo-cycloalkylimide group and an amino group are joined by a chain containing acetylenic unsaturation. The compounds are effective to antagonize the tremorogenic effect of oxotremorine and possess valuable pharmaceutical properties due to a strong central anti-cholinergic effect.

REFERENCES:
patent: 3354178 (1967-11-01), Dickinson
patent: 3856790 (1974-12-01), Freed et al.
C. R. Acad. Sc., Paris 264:2250-2253, (1967), Series D, Levy et al.

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