Oxothia compounds

Details Oxothia compounds Oxothia compounds

1979-11-09

1981-04-07

Randolph, John D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424263, 424270, 424272, 424275, 544204, 544214, 544236, 544240, 546274, 549 54, 549 55, C07D33364

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active

042607795

ABSTRACT:
Oxothia compounds, especially 2-oxo-2,3-dihydro-benzo[b]thiophene compounds of the formula ##STR1## in which Ph represents an optionally substituted 1,2-phenylene radical, X represents oxygen or sulphur, R.sub.1 represents an organic radical bonded via a carbon atom and R.sub.2 denotes hydrogen or an optionally substituted hydrocarbon radical of aliphatic character, and their salts are useful as peripheral analgetics and/or as antiphlogistic uricosuric and/or thrombolytic agents.

REFERENCES:
patent: 3413308 (1968-11-01), Bockstahler
patent: 3655693 (1972-04-01), Shen et al.
patent: 3971814 (1976-07-01), Stoss et al.
Kadin, J. Med. Chem. vol. 13, pp. 551-552 (1972).
Burger, Medicinal Chemistry, 2nd Ed., pp. 79-81, Interscience Publishers Inc. NY (1960).
Chemical Abstracts, vol. 88, abst. 88: 37601q (p. 484) (1978) (abst. of Ger. Offen. No. 2,713,584 pub. 10/20/77).

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