Oxophenyl-cyclohexyl-propanolamine derivatives, production...

Details Oxophenyl-cyclohexyl-propanolamine derivatives, production... Oxophenyl-cyclohexyl-propanolamine derivatives, production...

2003-05-26

2009-12-01

Chang, Celia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S211090, C514S230500, C514S375000, C514S651000, C540S546000, C546S226000, C548S217000

Reexamination Certificate

active

07625929

ABSTRACT:
The invention relates to the compounds of general formula (I)where R1represents H, a (C1-C4)alkyl, —CO(C1-C4)alkyl, (C1-C4)alkylphenyl or —CO-phenyl group, said phenyl being optionally substituted, R2represents H, a halogen atom, an —S(O)zR3, —NHSO2R3, —NHSO2-phenyl or —NHSO2—(C1-C4)alkylphenyl group where z is equal to 0, 1 or 2 and where R3represents a (C1-C4)alkyl group, said phenyl being optionally substituted;A is chosen fromwhere n is equal to 0, 1 or 2, R4and R5represent H, a (C1-C4)alkyl, hydroxyl, cyano, phenyl, benzyl, piperidyl, —CONH2, —CO-phenyl, —COOR3, —CH(phenyl) (OH) and —C(phenyl)2(OH) group, or R4and R5form together an optionally substituted 6-membered aromatic ring, R6represents H, a (C1-C4)alkyl, phenyl or benzyl group, and B represents a 5- or 6-membered nitrogen-containing heterocycle or homocycle optionally fused with a phenyl Group or optionally substituted; their addition salts; their method of preparation and their therapeutic application.

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