Oxoindanylpropionic acids and process for the preparation thereo

Details Oxoindanylpropionic acids and process for the preparation thereo Oxoindanylpropionic acids and process for the preparation thereo

1976-01-27

1977-02-08

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029362, 2605011, 260515R, 260515P, 260469, 42424853, 424267, 424308, 424316, C07D29500

Patent

active

040071790

ABSTRACT:
An oxoindanylpropionic acid having the formula ##STR1## wherein R represents ethyl group or isopropyl group and a salt thereof is prepared by reacting a dicarboxylic acid having the formula ##STR2## wherein R has the same meaning as defined above with a condensing agent, for example, sulfuric acid.
The oxoindanylpropionic acid is reduced to give the corresponding indanylpropionic acid which is useful as anti-inflammatory, analgesic and antipyretic agents.

REFERENCES:
patent: 3532752 (1970-10-01), Shen et al.
patent: 3644479 (1972-02-01), Juby et al.
patent: 3929872 (1975-12-01), Cragoe, Jr. et al.
patent: 3932498 (1976-01-01), Shen et al.
Rahman et al., Chem. Abst., vol. 78, 3990(u), 1973.
Yoshihira et al., Chem. Pharm. Bull., 19(7), 1491-1495 (1971).
Nambudiry et al., Chem. Abst., vol. 80, 121128(h)(74).
Huneck et al., Chem. Abst., vol. 71, 91132z (1969).

Affiliated with

Also associated with

Rating

Oxoindanylpropionic acids and process for the preparation thereo does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oxoindanylpropionic acids and process for the preparation thereo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxoindanylpropionic acids and process for the preparation thereo will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1212780