Oxoalkylpyridines

Details Oxoalkylpyridines Oxoalkylpyridines

1974-02-19

1976-09-14

Randolph, John D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424263, 2602948B, 2602948D, 2602948R, 260295F, 260295R, 260295T, 260296B, 260296T, 260296R, 260297B, 260297T, C07D21350

Patent

active

039806570

ABSTRACT:
New pyridine compounds of the general formula I ##EQU1## wherein R denotes an optionally substituted cycloaliphatic hydrocarbon radical, Ph denotes an ortho-phenylene radical or especially a para-phenylene radical, A denotes a lower alkylene radical or a direct bond, X denotes an optionally functionally modified oxo group and Py denotes a pyridine radical, are useful as fibrinolytics, thrombolytics, antiphlogistics and as mild analgesics.

REFERENCES:
patent: 3262937 (1966-07-01), Pesson
patent: 3373838 (1968-03-01), Stemple
patent: 3795677 (1974-03-01), Carr et al.
Burger et al., J. Am. Chem. Soc. vol. 72, pp. 1988-1990 (1950).
Miller et al., J. Am. Chem. Soc. vol. 78, pp. 674-678 (1956).
Hardtmann et al., J. Med. Chem. vol. 12, pp. 1093-1096 (1969).
Jephcott, J. Am. Chem. Soc. vol. 50, pp. 1189-1192 (1928).
Kloetzel et al., J. Am. Chem. Soc. vol. 79, pp. 4226-4229 (1957).
Conant, The Chemistry of Organic Compounds, pp. 470-471 and 481, The MacMillan Co. NY (1939) (Revised Edition).

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