Oxoalkanoic acid derivatives as inhibitors of angiotensin conver

Details Oxoalkanoic acid derivatives as inhibitors of angiotensin conver Oxoalkanoic acid derivatives as inhibitors of angiotensin conver

1980-12-24

1982-05-11

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424263, 424274, 546272, 548468, 548517, 548533, 549448, 549452, C07D20712, C07D20716, C07D40112, C07D40512

Patent

active

043294731

ABSTRACT:
This invention relates to novel analogs of proline terminal tripeptides and related compounds and is typified by ##STR1## The compounds are potent inhibitors of angiotensin converting enzyme and as such are useful as antihypertensive agents.

REFERENCES:
patent: 3141024 (1964-07-01), Houssin
patent: 4040889 (1977-09-01), Ondetti et al.
patent: 4091024 (1978-05-01), Ondetti
patent: 4113715 (1978-09-01), Ondetti et al.
patent: 4116962 (1978-09-01), Ondetti et al.
patent: 4127729 (1978-11-01), Ondetti
patent: 4128721 (1978-12-01), Ondetti
patent: 4154934 (1979-05-01), Bernstein et al.
patent: 4154936 (1979-05-01), Ondetti et al.
patent: 4154946 (1979-05-01), Ondetti et al.
Ondetti et al., Science, vol. 196, p. 441, (1977).
Cushman et al., Biochemistry, vol. 16, p. 5484, (1977).
Atkinson et al., Lancet, p. 557, (1979).

Affiliated with

Also associated with

Rating

Oxoalkanoic acid derivatives as inhibitors of angiotensin conver does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oxoalkanoic acid derivatives as inhibitors of angiotensin conver, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxoalkanoic acid derivatives as inhibitors of angiotensin conver will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-757056