(Oxo-pyrazolo[1,5a]pyrimidin-2-yl)alkyl-carboxamides

Details (Oxo-pyrazolo[1,5a]pyrimidin-2-yl)alkyl-carboxamides (Oxo-pyrazolo[1,5a]pyrimidin-2-yl)alkyl-carboxamides

2006-03-07

2006-03-07

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S267000

Reexamination Certificate

active

07008947

ABSTRACT:
Disclosed are compounds of the formulaand the pharmaceutically acceptable salts thereof where the variables R1, R2, A, R4, R5, R6, R6′, n, and W are defined herein. These compounds bind to the benzodiazepine site of GABAAreceptors are provided and, therefore can be used to modulate ligand binding to GABAAreceptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals and livestock animals.

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