Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1984-07-20
1987-08-25
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 46, 514 49, 514 50, 536 23, 536 24, 536 26, A61K 3170, C07H 1700
Patent
active
046893210
ABSTRACT:
Certain 3-oxo-prop-1-enyl purine and pyrimidine derivatives and the corresponding nucleosides have been prepared. These compounds exhibit interesting and valuable cytotoxic activity. This cytotoxicity is of special interest in that it appears to inhibit DNA reproduction without affecting RNA or protein synthesis.
REFERENCES:
patent: 3376283 (1968-04-01), Hunter
patent: 4171431 (1979-10-01), Skulnick
patent: 4267171 (1981-05-01), Bergstrom et al.
Grollman Arthur P.
Johnson Francis
Brown Johnnie R.
Rollins Jr. John W.
The Research Foundation of State University of New York
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