(Oxo-4-4H-(1)-benzopyran-8-yl) alkanoic acids, salts and derivat

Details (Oxo-4-4H-(1)-benzopyran-8-yl) alkanoic acids, salts and derivat (Oxo-4-4H-(1)-benzopyran-8-yl) alkanoic acids, salts and derivat

1984-11-06

1986-07-22

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549403, 549401, 549 60, 544151, 544146, 514444, 514236, 514230, A61K 3135, C07D31130, C07D31126, C07D31122

Patent

active

046020349

ABSTRACT:
The invention concerns: (oxo-4-4H-(1)-benzopyran-8-yl) alkanoic acids and their derivatives, their manufacture, represented by the formula: ##STR1## where Ar is hydrogen, a phenyl radical which may or may not be substituted, thenyl, furyl, naphthyl, a lower alkyl, cycloalkyl, aralkyl radical; B is a linear or branched lower alkyl radical, either saturated or ethylinically unsaturated; R.sub.1 is hydrogen or a phenyl radical; X is hydrogen or a lower alkyl or alkoxy radical and n=1, as well as salts, esters, aminoesters and amides.
Compounds and their derivatives may be used as medicines, in particular in the control of tumors.

REFERENCES:
patent: 2921070 (1960-01-01), Da Re
patent: 3770802 (1973-11-01), Sianesi
patent: 4079139 (1978-03-01), Gay
patent: 4097582 (1978-06-01), Briet et al.
patent: 4148900 (1979-04-01), Doria et al.

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