[Oxo-4-4H-[1]-benzopyran-8-yl]alcanoic acids, salts and derivati

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549403, 5142335, A61K 3135, C07D31126

Patent

active

047835338

ABSTRACT:
The invention concerns [oxo-4-4H-[1]-benzopyran-8-yl]-alcanoic acids and their derivatives, their manufacture, represented by the formula. ##STR1## where AR is hydrogen, a phenyl radical which may or may not be substituted thenyl, furyl, naphthyl, a lower alkyl, cycloalkyl, aralkyl radical; B is a linear or branched lower alkyl radical, either saturated or ethylinically unsaturated; R.sub.1 is hydrogen or a phenyl radical; X is hydrogen or a lower alkyl or alkoxy radical and n=1, as well as salts, esters, aminoesters and amides.
Compounds and their derivatives may be used as medicines, in particular in the control of tumors.

REFERENCES:
patent: 2921070 (1960-01-01), Da Re
patent: 3770802 (1973-11-01), Sianesi
patent: 4079139 (1978-03-01), Gay
patent: 4097582 (1978-06-01), Briet et al.
patent: 4148900 (1979-04-01), Doria et al.

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