Oxindoledioxans, synthesis thereof, and intermediates thereto

Details Oxindoledioxans, synthesis thereof, and intermediates thereto Oxindoledioxans, synthesis thereof, and intermediates thereto

2007-05-25

2010-02-16

Shameem, Golam M M (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S200000, C549S356000, C549S358000, C549S362000, C548S427000, C548S429000, C548S430000, C548S431000

Reexamination Certificate

active

07662979

ABSTRACT:
The present invention provides methods for preparing compounds having activity as dopamine autoreceptor agonists and partial agonists at the postsynaptic dopamine D2receptor. These compounds are useful for treating dopaminergic disorders, such as schizophrenia, schizoaffective disorder, Parkinson's disease, Tourette's syndrome, hyperprolactinemia, and drug addiction.

REFERENCES:
patent: 4314944 (1982-02-01), Huffman et al.
patent: 5126366 (1992-06-01), Stack et al.
patent: 5166367 (1992-11-01), Stack et al.
patent: 5189171 (1993-02-01), Stack et al.
patent: 5235055 (1993-08-01), Stack et al.
patent: 5245051 (1993-09-01), Stack et al.
patent: 5318988 (1994-06-01), Schohe-Loop et al.
patent: 5371094 (1994-12-01), Heine et al.
patent: 5750556 (1998-05-01), Mewshaw et al.
patent: 5756532 (1998-05-01), Stack et al.
patent: 5869490 (1999-02-01), Stack et al.
patent: 5914263 (1999-06-01), Buizer et al.
patent: 5962465 (1999-10-01), Stack et al.
patent: 6700001 (2004-03-01), Gross et al.
patent: 6716998 (2004-04-01), Gross et al.
patent: 7135479 (2006-11-01), Zhou et al.
patent: 4135474 (1993-04-01), None
patent: 0771800 (1998-01-01), None
patent: 0771801 (1999-03-01), None
patent: 0939135 (1999-09-01), None
patent: 0707007 (2001-12-01), None
patent: 1375503 (2004-01-01), None
patent: WO 0771800 (1991-09-01), None
Michael D. Ennis, et al., J. Med. Chem., 35, 3058-3066, (1992).
Joule et al., Heterocyclic Chemistry, 3d Ed. (1995 Stanley Thorne Ltd, Uk), 327-328, (1995).
Lilian Radesca et al., J. Med. Chem., 34, 3058-3065, (1991).
Panico et al., A Guide to IUPAC Nomenclature of Organic Compound (Recommendations) (1993).
I.L. Finar, Organic Chemistry, Vol. I, 721-722, (1959).
Beckett et al., Tetrahedron, 24, 6093-6109, (1968).
Heinrich et al., European Journal of Pharmacology, 552, 36-45, (2006).
Lahti et al., Molecular Pharmacology, 42, 432-438, (1992).
Tammingra et al., Archives of General Psychiatry, 43(4), 398-402, (1986).
Tammingra et al., Science, 200, 567-568, (1978).
M Makosza et al., J. Org. Chem., 48, 3860-3861, (1983).
M. Makosza et al., Synthesis, 1409-1410, (1994).
M. Makosza et al., Tetrahedron, 51(26), 7277-7286, (1995).
Galante et al., The 236thACS Natl. Meeting, Phila, Pa, Aug. 17-21, 2008.
Mills et al., J. Chem. Soc., 2510-2524, (1930).
Corsini et al., Advances in Biochemical Psychopharmacology, 16, 645-648, (1977).
International Search Report, PCT/US2007/012622, mailed on Oct. 26, 2007.

Affiliated with

Also associated with

Rating

Oxindoledioxans, synthesis thereof, and intermediates thereto does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oxindoledioxans, synthesis thereof, and intermediates thereto, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxindoledioxans, synthesis thereof, and intermediates thereto will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4164692