Oximes of 3'"-dehydrocardenolide tridigitoxosides

Details Oximes of 3'"-dehydrocardenolide tridigitoxosides Oximes of 3'"-dehydrocardenolide tridigitoxosides

1982-11-05

1984-07-24

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugate includes potentiator; or composition comprising...

536 61, A61J 31705, C07J 1900

Patent

active

044617631

ABSTRACT:
The present invention provides 3'"-dehydrocardenolide tridigitoxoside oximes of the general formula: ##STR1## in which R.sub.1 is a hydrogen atom or an alkyl radical containing up to 3 carbon atoms, R.sub.2 is a hydrogen atom or a lower acyl or alkyl radical and R.sub.3 represents two hydrogen atoms, the group ##STR2## or the oximino group .dbd.NOR.sub.1, wherein R.sub.1 has the above-given meaning.
The present invention also provides a process for the preparation of these oximes, as well as pharmaceutical compostions containing them which are useful for the treatment of cardiac insufficiency.

REFERENCES:
patent: 3981862 (1976-07-01), Voigtlander et al.
patent: 4021546 (1977-05-01), Bodor

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