Oximes of 11-(3-oxooctyl)-hexahydro-2,6-methano-3-benzazocines

Details Oximes of 11-(3-oxooctyl)-hexahydro-2,6-methano-3-benzazocines Oximes of 11-(3-oxooctyl)-hexahydro-2,6-methano-3-benzazocines

1981-03-12

1982-06-15

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D22126

Patent

active

043352430

ABSTRACT:
6(eq)-R.sub.4 -1,2,3,4,5,6-Hexahydro-3-R.sub.1 -11(ax)-R.sub.3 -11(eq)-CH.sub.2 Z-2,6-methano-3-benzazocines, useful as analgesic agents and narcotic antagonists, prepared by heating, with formic acid in an organic solvent or with certain ammonium formates in the absence of a solvent, certain 1,2,3,4,4a,5,10,10a-octahydro-2,5-methanobenzo[g]quinolines.

REFERENCES:
patent: 2924603 (1960-02-01), Gordon et al.
patent: 3932422 (1976-01-01), Michne
Bentley, J. Am. Chem. Soc. 89, 3267-3292 (1967).

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